Pandemic is set in the near future, where a virus of epic proportions has overtaken the planet. There are more infected than uninfected, and humanity is losing its grip on survival. Its only hope is finding a cure and keeping the infected contained. Lauren (Rachel Nichols) is a doctor, who, after the fall of New York, comes to Los Angeles to lead a team to hunt for and rescue uninfected survivors.

Fueled by revenge, Michael sets up a meeting with Clef Robie, the man who murdered his wife and child 6 years ago. His plans of killing him come to a standstill when two gunmen rob the diner. Michael takes matters into his own hands when he shoots them and holds the entire diner hostage until he kills his target.

Cole is a likeable regular guy. Except that ever since he witnessed a gruesome murder-suicide, things haven't been quite right. His wife left him, he is tormented by hallucinations and his career has nosedived into a blue collar job with a carpet cleaning service. Just when it seems his life has reached bottom, Cole is called out on an all-night cleaning job in an Italianate mansion far from the city. For company he has Henry, the rich, condescending homeowner who seems to take sadistic pleasure in letting Cole think he has just murdered his wife. A reddish stain on the carpet, a knife hacking into baked rabbit, a cell phone that won't stop ringing - does it add up to murder or is Cole losing his last handhold on his fragile sanity?